Small acidic protein (SMAP)
Homo sapiens — UniProt O00193
Data last refreshed: (UniProt release unknown)
Key facts
Small acidic protein (SMAP) is a protein from Homo sapiens identified by UniProt accession O00193, 183 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: O00193; gene symbol SMAP.
- Organism: Homo sapiens.
- Length: 183 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, reticulocyte count and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small acidic protein |
|---|---|
| UniProt accession | O00193 |
| Gene | SMAP |
| Organism | Homo sapiens |
| Length | 183 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.44
- reticulocyte count · score 0.43
- mean corpuscular hemoglobin · score 0.43
- heel bone mineral density · score 0.43
- erythrocyte count · score 0.41
- bone quantitative ultrasound measurement · score 0.37
- neurodegenerative disease · score 0.36
- bone density · score 0.35
- red blood cell density measurement · score 0.34
- mean corpuscular hemoglobin concentration · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O00193-F1 | alphafold | PREDICTED | 65.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O00193.
Amino-acid sequence (183 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMAP?
The strongest Open Targets associations for SMAP are mean corpuscular volume, reticulocyte count, mean corpuscular hemoglobin, heel bone mineral density and erythrocyte count.
How long is the SMAP protein?
The Homo sapiens SMAP protein (UniProt O00193) is 183 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O00193 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O00193 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.