Transcription factor SOX-1 (SOX1)
Homo sapiens — UniProt O00570
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-1 (SOX1) is a protein from Homo sapiens identified by UniProt accession O00570, 391 residues long. MolForge cross-references it against 0 known binders and 171 disease associations.
- UniProt accession: O00570; gene symbol SOX1.
- Organism: Homo sapiens.
- Length: 391 amino acids.
- Top disease associations (Open Targets): testosterone measurement, gut microbiome measurement and insomnia measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-1 |
|---|---|
| UniProt accession | O00570 |
| Gene | SOX1 |
| Organism | Homo sapiens |
| Length | 391 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (171)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.41
- gut microbiome measurement · score 0.36
- insomnia measurement · score 0.25
- neoplasm · score 0.11
- cancer · score 0.10
- calf circumference measurement · score 0.08
- cholangiocarcinoma · score 0.07
- colorectal carcinoma · score 0.07
- cervical adenocarcinoma · score 0.07
- glioblastoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O00570-F1 | alphafold | PREDICTED | 56.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O00570.
Amino-acid sequence (391 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX1?
The strongest Open Targets associations for SOX1 are testosterone measurement, gut microbiome measurement, insomnia measurement, neoplasm and cancer.
How long is the SOX1 protein?
The Homo sapiens SOX1 protein (UniProt O00570) is 391 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O00570 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O00570 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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