Syntaphilin (SNPH)
Homo sapiens — UniProt O15079
Data last refreshed: (UniProt release unknown)
Key facts
Syntaphilin (SNPH) is a protein from Homo sapiens identified by UniProt accession O15079, 494 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: O15079; gene symbol SNPH.
- Organism: Homo sapiens.
- Length: 494 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Syntaphilin |
|---|---|
| UniProt accession | O15079 |
| Gene | SNPH |
| Organism | Homo sapiens |
| Length | 494 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- blood protein measurement · score 0.19
- mean platelet volume · score 0.07
- glomerular filtration rate · score 0.05
- attention deficit hyperactivity disorder · score 0.04
- glioblastoma multiforme · score 0.03
- atypical teratoid rhabdoid tumor · score 0.03
- medulloblastoma · score 0.02
- ulcerative colitis · score 0.02
- neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O15079-F1 | alphafold | PREDICTED | 60.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O15079.
Amino-acid sequence (494 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNPH?
The strongest Open Targets associations for SNPH are neurodegenerative disease, blood protein measurement, mean platelet volume, glomerular filtration rate and attention deficit hyperactivity disorder.
How long is the SNPH protein?
The Homo sapiens SNPH protein (UniProt O15079) is 494 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O15079 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O15079 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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