Transcription factor SOX-12 (SOX12)
Homo sapiens — UniProt O15370
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-12 (SOX12) is a protein from Homo sapiens identified by UniProt accession O15370, 315 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: O15370; gene symbol SOX12.
- Organism: Homo sapiens.
- Length: 315 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, calf circumference measurement and lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-12 |
|---|---|
| UniProt accession | O15370 |
| Gene | SOX12 |
| Organism | Homo sapiens |
| Length | 315 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.06
- calf circumference measurement · score 0.02
- lung carcinoma · score 0.01
- Sepsis · score 0.00
- neoplasm · score 0.00
- colorectal cancer · score 0.00
- nonpapillary renal cell carcinoma · score 0.00
- multiple myeloma · score 0.00
- Systemic lupus erythematosus · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O15370-F1 | alphafold | PREDICTED | 63.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O15370.
Amino-acid sequence (315 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX12?
The strongest Open Targets associations for SOX12 are hepatocellular carcinoma, calf circumference measurement, lung carcinoma, Sepsis and neoplasm.
How long is the SOX12 protein?
The Homo sapiens SOX12 protein (UniProt O15370) is 315 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O15370 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O15370 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.