Zinc finger protein SNAI2 (SNAI2)
Homo sapiens — UniProt O43623
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein SNAI2 (SNAI2) is a protein from Homo sapiens identified by UniProt accession O43623, 268 residues long. MolForge cross-references it against 0 known binders and 532 disease associations.
- UniProt accession: O43623; gene symbol SNAI2.
- Organism: Homo sapiens.
- Length: 268 amino acids.
- Top disease associations (Open Targets): piebaldism, Waardenburg syndrome type 2 and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein SNAI2 |
|---|---|
| UniProt accession | O43623 |
| Gene | SNAI2 |
| Organism | Homo sapiens |
| Length | 268 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (532)
Diseases linked to this target (Open Targets).
- piebaldism · score 0.52
- Waardenburg syndrome type 2 · score 0.42
- neoplasm · score 0.12
- hepatocellular carcinoma · score 0.11
- glioblastoma multiforme · score 0.11
- esophageal squamous cell carcinoma · score 0.11
- cancer · score 0.11
- melanoma · score 0.10
- head and neck squamous cell carcinoma · score 0.10
- oral squamous cell carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O43623-F1 | alphafold | PREDICTED | 64.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O43623.
Amino-acid sequence (268 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNAI2?
The strongest Open Targets associations for SNAI2 are piebaldism, Waardenburg syndrome type 2, neoplasm, hepatocellular carcinoma and glioblastoma multiforme.
How long is the SNAI2 protein?
The Homo sapiens SNAI2 protein (UniProt O43623) is 268 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O43623 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O43623 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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