Transcription factor SOX-15 (SOX15)
Homo sapiens — UniProt O60248
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-15 (SOX15) is a protein from Homo sapiens identified by UniProt accession O60248, 233 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: O60248; gene symbol SOX15.
- Organism: Homo sapiens.
- Length: 233 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, testosterone measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-15 |
|---|---|
| UniProt accession | O60248 |
| Gene | SOX15 |
| Organism | Homo sapiens |
| Length | 233 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- testosterone measurement · score 0.18
- monocyte count · score 0.15
- congenital disorder of glycosylation · score 0.12
- MPDU1-congenital disorder of glycosylation · score 0.12
- Calcium channel blocker use measurement · score 0.12
- Red cell distribution width · score 0.11
- apolipoprotein A 1 measurement · score 0.10
- mean platelet volume · score 0.09
- sex hormone-binding globulin measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O60248-F1 | alphafold | PREDICTED | 66.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O60248.
Amino-acid sequence (233 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX15?
The strongest Open Targets associations for SOX15 are neurodegenerative disease, testosterone measurement, monocyte count, congenital disorder of glycosylation and MPDU1-congenital disorder of glycosylation.
How long is the SOX15 protein?
The Homo sapiens SOX15 protein (UniProt O60248) is 233 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O60248 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O60248 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.