Serine/threonine-protein kinase 17B (STK17B)
Homo sapiens — UniProt O94768
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase 17B (STK17B) is a protein from Homo sapiens identified by UniProt accession O94768, 372 residues long. MolForge cross-references it against 9 known binders and 104 disease associations.
- UniProt accession: O94768; gene symbol STK17B.
- Organism: Homo sapiens.
- Length: 372 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, eosinophil count and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase 17B |
|---|---|
| UniProt accession | O94768 |
| Gene | STK17B |
| Organism | Homo sapiens |
| Length | 372 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (104)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.48
- eosinophil count · score 0.45
- Red cell distribution width · score 0.43
- mean corpuscular hemoglobin concentration · score 0.42
- mean corpuscular hemoglobin · score 0.41
- mean reticulocyte volume · score 0.39
- eosinophil percentage of leukocytes · score 0.37
- cortical thickness · score 0.33
- reticulocyte count · score 0.28
- heel bone mineral density · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O94768-F1 | alphafold | PREDICTED | 81.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O94768.
Amino-acid sequence (372 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STK17B?
The strongest Open Targets associations for STK17B are mean corpuscular volume, eosinophil count, Red cell distribution width, mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin.
How long is the STK17B protein?
The Homo sapiens STK17B protein (UniProt O94768) is 372 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O94768 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O94768 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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