SLIT and NTRK-like protein 3 (SLITRK3)
Homo sapiens — UniProt O94933
Data last refreshed: (UniProt release unknown)
Key facts
SLIT and NTRK-like protein 3 (SLITRK3) is a protein from Homo sapiens identified by UniProt accession O94933, 977 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: O94933; gene symbol SLITRK3.
- Organism: Homo sapiens.
- Length: 977 amino acids.
- Top disease associations (Open Targets): blood protein measurement, Intellectual disability and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SLIT and NTRK-like protein 3 |
|---|---|
| UniProt accession | O94933 |
| Gene | SLITRK3 |
| Organism | Homo sapiens |
| Length | 977 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.38
- Intellectual disability · score 0.33
- type 2 diabetes mellitus · score 0.25
- diabetic nephropathy · score 0.25
- protein measurement · score 0.21
- PHF-tau measurement · score 0.20
- drug use measurement · score 0.12
- estradiol measurement · score 0.05
- gastrointestinal stromal tumor · score 0.03
- age at onset · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O94933-F1 | alphafold | PREDICTED | 63.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O94933.
Amino-acid sequence (977 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLITRK3?
The strongest Open Targets associations for SLITRK3 are blood protein measurement, Intellectual disability, type 2 diabetes mellitus, diabetic nephropathy and protein measurement.
How long is the SLITRK3 protein?
The Homo sapiens SLITRK3 protein (UniProt O94933) is 977 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O94933 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O94933 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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