Protein HEXIM1 (HEXIM1)
Homo sapiens — UniProt O94992
Data last refreshed: (UniProt release unknown)
Key facts
Protein HEXIM1 (HEXIM1) is a protein from Homo sapiens identified by UniProt accession O94992, 359 residues long. MolForge cross-references it against 0 known binders and 180 disease associations.
- UniProt accession: O94992; gene symbol HEXIM1.
- Organism: Homo sapiens.
- Length: 359 amino acids.
- Top disease associations (Open Targets): lean body mass, neurodegenerative disease and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein HEXIM1 |
|---|---|
| UniProt accession | O94992 |
| Gene | HEXIM1 |
| Organism | Homo sapiens |
| Length | 359 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (180)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.38
- neurodegenerative disease · score 0.37
- fat body mass · score 0.31
- insomnia · score 0.29
- systolic blood pressure · score 0.27
- cystatin C measurement · score 0.26
- base metabolic rate measurement · score 0.25
- whole body water mass · score 0.25
- body height · score 0.21
- appendicular lean mass · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O94992-F1 | alphafold | PREDICTED | 65.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O94992.
Amino-acid sequence (359 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HEXIM1?
The strongest Open Targets associations for HEXIM1 are lean body mass, neurodegenerative disease, fat body mass, insomnia and systolic blood pressure.
How long is the HEXIM1 protein?
The Homo sapiens HEXIM1 protein (UniProt O94992) is 359 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O94992 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O94992 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.