About Protein HEXIM1
Protein HEXIM1 (HEXIM1) is a protein
from Homo sapiens identified by UniProt accession
O94992, 359 residues long.
MolForge cross-references it against 0 known binders and
180 disease associations.
Target properties
| Protein name | Protein HEXIM1 |
|---|
| UniProt accession | O94992 |
|---|
| Gene | HEXIM1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 359 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (180)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.38
- neurodegenerative disease · score 0.37
- fat body mass · score 0.31
- insomnia · score 0.29
- systolic blood pressure · score 0.27
- cystatin C measurement · score 0.26
- base metabolic rate measurement · score 0.25
- whole body water mass · score 0.25
- body height · score 0.21
- appendicular lean mass · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O94992-F1 | alphafold | PREDICTED | 65.56 | — |
Amino-acid sequence (359 residues)
MAEPFLSEYQ HQPQTSNCTG AAAVQEELNP ERPPGAEERV PEEDSRWQSR AFPQLGGRPG PEGEGSLESQ PPPLQTQACP ESSCLREGEK GQNGDDSSAG GDFPPPAEVE PTPEAELLAQ PCHDSEASKL GAPAAGGEEE WGQQQRQLGK KKHRRRPSKK KRHWKPYYKL TWEEKKKFDE KQSLRASRIR AEMFAKGQPV APYNTTQFLM DDHDQEEPDL KTGLYSKRAA AKSDDTSDDD FMEEGGEEDG GSDGMGGDGS EFLQRDFSET YERYHTESLQ NMSKQELIKE YLELEKCLSR MEDENNRLRL ESKRLGGDDA RVRELELELD RLRAENLQLL TENELHRQQE RAPLSKFGD
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