Transcription factor SOX-30 (SOX30)
Homo sapiens — UniProt O94993
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-30 (SOX30) is a protein from Homo sapiens identified by UniProt accession O94993, 753 residues long. MolForge cross-references it against 0 known binders and 164 disease associations.
- UniProt accession: O94993; gene symbol SOX30.
- Organism: Homo sapiens.
- Length: 753 amino acids.
- Top disease associations (Open Targets): protein measurement, male infertility and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-30 |
|---|---|
| UniProt accession | O94993 |
| Gene | SOX30 |
| Organism | Homo sapiens |
| Length | 753 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (164)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.40
- male infertility · score 0.26
- mean corpuscular hemoglobin concentration · score 0.18
- neoplasm · score 0.11
- azoospermia · score 0.10
- AIDS dementia · score 0.10
- partial chromosome Y deletion · score 0.10
- PHF-tau measurement · score 0.09
- male infertility with teratozoospermia due to single gene mutation · score 0.09
- non-small cell lung carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O94993-F1 | alphafold | PREDICTED | 49.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O94993.
Amino-acid sequence (753 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX30?
The strongest Open Targets associations for SOX30 are protein measurement, male infertility, mean corpuscular hemoglobin concentration, neoplasm and azoospermia.
How long is the SOX30 protein?
The Homo sapiens SOX30 protein (UniProt O94993) is 753 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O94993 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O94993 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.