Sorting nexin-4 (SNX4)
Homo sapiens — UniProt O95219
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-4 (SNX4) is a protein from Homo sapiens identified by UniProt accession O95219, 450 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: O95219; gene symbol SNX4.
- Organism: Homo sapiens.
- Length: 450 amino acids.
- Top disease associations (Open Targets): creatinine measurement, body height and vitamin D measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-4 |
|---|---|
| UniProt accession | O95219 |
| Gene | SNX4 |
| Organism | Homo sapiens |
| Length | 450 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.23
- body height · score 0.16
- vitamin D measurement · score 0.15
- urate measurement · score 0.14
- glomerular filtration rate · score 0.10
- acute myocardial infarction · score 0.01
- Kidney Oncocytoma · score 0.01
- IGA glomerulonephritis · score 0.01
- neoplasm · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95219-F1 | alphafold | PREDICTED | 83.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95219.
Amino-acid sequence (450 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX4?
The strongest Open Targets associations for SNX4 are creatinine measurement, body height, vitamin D measurement, urate measurement and glomerular filtration rate.
How long is the SNX4 protein?
The Homo sapiens SNX4 protein (UniProt O95219) is 450 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95219 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95219 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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