Pre-mRNA-splicing factor SLU7 (SLU7)
Homo sapiens — UniProt O95391
Data last refreshed: (UniProt release unknown)
Key facts
Pre-mRNA-splicing factor SLU7 (SLU7) is a protein from Homo sapiens identified by UniProt accession O95391, 586 residues long. MolForge cross-references it against 0 known binders and 188 disease associations.
- UniProt accession: O95391; gene symbol SLU7.
- Organism: Homo sapiens.
- Length: 586 amino acids.
- Top disease associations (Open Targets): eosinophil count, asthma and systemic lupus erythematosus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Pre-mRNA-splicing factor SLU7 |
|---|---|
| UniProt accession | O95391 |
| Gene | SLU7 |
| Organism | Homo sapiens |
| Length | 586 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (188)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.25
- asthma · score 0.20
- systemic lupus erythematosus · score 0.19
- eosinophil percentage of leukocytes · score 0.17
- allergic rhinitis · score 0.16
- Eczematoid dermatitis · score 0.16
- allergic disease · score 0.13
- neurofibrillary tangles measurement · score 0.12
- Inhalant adrenergic use measurement · score 0.12
- seasonal allergic rhinitis · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95391-F1 | alphafold | PREDICTED | 75.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95391.
Amino-acid sequence (586 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLU7?
The strongest Open Targets associations for SLU7 are eosinophil count, asthma, systemic lupus erythematosus, eosinophil percentage of leukocytes and allergic rhinitis.
How long is the SLU7 protein?
The Homo sapiens SLU7 protein (UniProt O95391) is 586 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95391 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95391 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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