Transcription factor SOX-14 (SOX14)
Homo sapiens — UniProt O95416
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-14 (SOX14) is a protein from Homo sapiens identified by UniProt accession O95416, 240 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: O95416; gene symbol SOX14.
- Organism: Homo sapiens.
- Length: 240 amino acids.
- Top disease associations (Open Targets): bone density, urate measurement and adolescent idiopathic scoliosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-14 |
|---|---|
| UniProt accession | O95416 |
| Gene | SOX14 |
| Organism | Homo sapiens |
| Length | 240 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- bone density · score 0.33
- urate measurement · score 0.33
- adolescent idiopathic scoliosis · score 0.27
- Crohn's disease · score 0.26
- prostate carcinoma · score 0.25
- sclerosing cholangitis · score 0.25
- ulcerative colitis · score 0.25
- psoriasis · score 0.25
- ankylosing spondylitis · score 0.25
- protein measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95416-F1 | alphafold | PREDICTED | 66.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95416.
Amino-acid sequence (240 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX14?
The strongest Open Targets associations for SOX14 are bone density, urate measurement, adolescent idiopathic scoliosis, Crohn's disease and prostate carcinoma.
How long is the SOX14 protein?
The Homo sapiens SOX14 protein (UniProt O95416) is 240 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95416 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95416 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.