Lymphocyte antigen 86 (LY86)
Homo sapiens — UniProt O95711
Data last refreshed: (UniProt release unknown)
Key facts
Lymphocyte antigen 86 (LY86) is a protein from Homo sapiens identified by UniProt accession O95711, 162 residues long. MolForge cross-references it against 0 known binders and 277 disease associations.
- UniProt accession: O95711; gene symbol LY86.
- Organism: Homo sapiens.
- Length: 162 amino acids.
- Top disease associations (Open Targets): urate measurement, reticulocyte count and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lymphocyte antigen 86 |
|---|---|
| UniProt accession | O95711 |
| Gene | LY86 |
| Organism | Homo sapiens |
| Length | 162 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (277)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.40
- reticulocyte count · score 0.40
- BMI-adjusted waist-hip ratio · score 0.37
- waist-hip ratio · score 0.36
- physical activity measurement · score 0.35
- BMI-adjusted hip circumference · score 0.35
- reticulocyte measurement · score 0.34
- venous thromboembolism · score 0.34
- heel bone mineral density · score 0.33
- FEV/FVC ratio · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95711-F1 | alphafold | PREDICTED | 87.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95711.
Amino-acid sequence (162 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LY86?
The strongest Open Targets associations for LY86 are urate measurement, reticulocyte count, BMI-adjusted waist-hip ratio, waist-hip ratio and physical activity measurement.
How long is the LY86 protein?
The Homo sapiens LY86 protein (UniProt O95711) is 162 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95711 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95711 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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