Serine/threonine-protein kinase OSR1 (OXSR1)
Homo sapiens — UniProt O95747
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase OSR1 (OXSR1) is a protein from Homo sapiens identified by UniProt accession O95747, 527 residues long. MolForge cross-references it against 4 known binders and 44 disease associations.
- UniProt accession: O95747; gene symbol OXSR1.
- Organism: Homo sapiens.
- Length: 527 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, neuroinflammatory disorder and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase OSR1 |
|---|---|
| UniProt accession | O95747 |
| Gene | OXSR1 |
| Organism | Homo sapiens |
| Length | 527 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.34
- neuroinflammatory disorder · score 0.34
- neurodegenerative disease · score 0.32
- mean corpuscular hemoglobin concentration · score 0.29
- mean corpuscular volume · score 0.27
- taxonomic microbiome measurement · score 0.23
- gut microbiome measurement · score 0.23
- reticulocyte measurement · score 0.22
- mean reticulocyte volume · score 0.20
- arterial stiffness measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95747-F1 | alphafold | PREDICTED | 76.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95747.
Amino-acid sequence (527 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OXSR1?
The strongest Open Targets associations for OXSR1 are Red cell distribution width, neuroinflammatory disorder, neurodegenerative disease, mean corpuscular hemoglobin concentration and mean corpuscular volume.
How long is the OXSR1 protein?
The Homo sapiens OXSR1 protein (UniProt O95747) is 527 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95747 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95747 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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