Tetraspanin-15 (TSPAN15)
Homo sapiens — UniProt O95858
Data last refreshed: (UniProt release unknown)
Key facts
Tetraspanin-15 (TSPAN15) is a protein from Homo sapiens identified by UniProt accession O95858, 294 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: O95858; gene symbol TSPAN15.
- Organism: Homo sapiens.
- Length: 294 amino acids.
- Top disease associations (Open Targets): venous thromboembolism, deep vein thrombosis and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tetraspanin-15 |
|---|---|
| UniProt accession | O95858 |
| Gene | TSPAN15 |
| Organism | Homo sapiens |
| Length | 294 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- venous thromboembolism · score 0.49
- deep vein thrombosis · score 0.45
- reticulocyte count · score 0.43
- pulmonary embolism · score 0.38
- reticulocyte measurement · score 0.38
- neutrophil count · score 0.36
- Immature Reticulocyte Fraction Measurement · score 0.32
- Thrombophlebitis · score 0.31
- Phlebitis · score 0.31
- total blood protein measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95858-F1 | alphafold | PREDICTED | 87.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95858.
Amino-acid sequence (294 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSPAN15?
The strongest Open Targets associations for TSPAN15 are venous thromboembolism, deep vein thrombosis, reticulocyte count, pulmonary embolism and reticulocyte measurement.
How long is the TSPAN15 protein?
The Homo sapiens TSPAN15 protein (UniProt O95858) is 294 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95858 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95858 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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