Lymphocyte antigen 6 complex locus protein G6d (LY6G6D)
Homo sapiens — UniProt O95868
Data last refreshed: (UniProt release unknown)
Key facts
Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) is a protein from Homo sapiens identified by UniProt accession O95868, 133 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: O95868; gene symbol LY6G6D.
- Organism: Homo sapiens.
- Length: 133 amino acids.
- Top disease associations (Open Targets): sphingolipid measurement, blood protein measurement and colorectal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lymphocyte antigen 6 complex locus protein G6d |
|---|---|
| UniProt accession | O95868 |
| Gene | LY6G6D |
| Organism | Homo sapiens |
| Length | 133 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- sphingolipid measurement · score 0.16
- blood protein measurement · score 0.11
- colorectal carcinoma · score 0.06
- familial pseudohyperkalemia · score 0.04
- neoplasm · score 0.04
- thrombocytopenia 4 · score 0.04
- platelet-type bleeding disorder 15 · score 0.04
- bleeding disorder, platelet-type, 24 · score 0.03
- thrombocytopenia 7 · score 0.03
- thrombocytopenia 2 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95868-F1 | alphafold | PREDICTED | 66.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95868.
Amino-acid sequence (133 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LY6G6D?
The strongest Open Targets associations for LY6G6D are sphingolipid measurement, blood protein measurement, colorectal carcinoma, familial pseudohyperkalemia and neoplasm.
How long is the LY6G6D protein?
The Homo sapiens LY6G6D protein (UniProt O95868) is 133 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95868 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95868 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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