Formimidoyltransferase-cyclodeaminase (FTCD)
Homo sapiens — UniProt O95954
Data last refreshed: (UniProt release unknown)
Key facts
Formimidoyltransferase-cyclodeaminase (FTCD) is a protein from Homo sapiens identified by UniProt accession O95954, 541 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: O95954; gene symbol FTCD.
- Organism: Homo sapiens.
- Length: 541 amino acids.
- Top disease associations (Open Targets): formiminoglutamic aciduria, genetic disorder and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Formimidoyltransferase-cyclodeaminase |
|---|---|
| UniProt accession | O95954 |
| Gene | FTCD |
| Organism | Homo sapiens |
| Length | 541 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- formiminoglutamic aciduria · score 0.77
- genetic disorder · score 0.49
- neurodegenerative disease · score 0.38
- Alzheimer disease · score 0.32
- Parkinson disease · score 0.32
- lysosomal storage disease · score 0.32
- multiple sclerosis · score 0.32
- Red cell distribution width · score 0.30
- BMI-adjusted waist-hip ratio · score 0.29
- blood protein measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-O95954-F1 | alphafold | PREDICTED | 95.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for O95954.
Amino-acid sequence (541 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FTCD?
The strongest Open Targets associations for FTCD are formiminoglutamic aciduria, genetic disorder, neurodegenerative disease, Alzheimer disease and Parkinson disease.
How long is the FTCD protein?
The Homo sapiens FTCD protein (UniProt O95954) is 541 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB O95954 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB O95954 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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