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Alpha-fetoprotein (AFP)

Homo sapiens — UniProt P02771

Gene: AFPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Alpha-fetoprotein (AFP) is a protein from Homo sapiens identified by UniProt accession P02771, 609 residues long. MolForge cross-references it against 0 known binders and 916 disease associations.

  • UniProt accession: P02771; gene symbol AFP.
  • Organism: Homo sapiens.
  • Length: 609 amino acids.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAlpha-fetoprotein
UniProt accessionP02771
GeneAFP
OrganismHomo sapiens
Length609 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P02771-F1alphafoldPREDICTED88.91—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for P02771.

Amino-acid sequence (609 residues)

MKWVESIFLI FLLNFTESRT LHRNEYGIAS ILDSYQCTAE ISLADLATIF FAQFVQEATY KEVSKMVKDA LTAIEKPTGD EQSSGCLENQ LPAFLEELCH EKEILEKYGH SDCCSQSEEG RHNCFLAHKK PTPASIPLFQ VPEPVTSCEA YEEDRETFMN KFIYEIARRH PFLYAPTILL WAARYDKIIP SCCKAENAVE CFQTKAATVT KELRESSLLN QHACAVMKNF GTRTFQAITV TKLSQKFTKV NFTEIQKLVL DVAHVHEHCC RGDVLDCLQD GEKIMSYICS QQDTLSNKIT ECCKLTTLER GQCIIHAEND EKPEGLSPNL NRFLGDRDFN QFSSGEKNIF LASFVHEYSR RHPQLAVSVI LRVAKGYQEL LEKCFQTENP LECQDKGEEE LQKYIQESQA LAKRSCGLFQ KLGEYYLQNA FLVAYTKKAP QLTSSELMAI TRKMAATAAT CCQLSEDKLL ACGEGAADII IGHLCIRHEM TPVNPGVGQC CTSSYANRRP CFSSLVVDET YVPPAFSDDK FIFHKDLCQA QGVALQTMKQ EFLINLVKQK PQITEEQLEA VIADFSGLLE KCCQGQEQEV CFAEEGQKLI SKTRAALGV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How long is the AFP protein?

The Homo sapiens AFP protein (UniProt P02771) is 609 amino acids long.

Browse: Targets: A · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtP02771
GeneAFP
OrganismHomo sapiens
Length609
Binders0
Diseases916
View on UniProt