Submaxillary gland androgen-regulated protein 3B (SMR3B)
Homo sapiens — UniProt P02814
Data last refreshed: (UniProt release unknown)
Key facts
Submaxillary gland androgen-regulated protein 3B (SMR3B) is a protein from Homo sapiens identified by UniProt accession P02814, 79 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: P02814; gene symbol SMR3B.
- Organism: Homo sapiens.
- Length: 79 amino acids.
- Top disease associations (Open Targets): eye infection, dental caries and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Submaxillary gland androgen-regulated protein 3B |
|---|---|
| UniProt accession | P02814 |
| Gene | SMR3B |
| Organism | Homo sapiens |
| Length | 79 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- eye infection · score 0.03
- dental caries · score 0.01
- hepatocellular carcinoma · score 0.01
- neoplasm · score 0.01
- small cell lung carcinoma · score 0.00
- prostate adenocarcinoma · score 0.00
- triple-negative breast cancer · score 0.00
- cancer · score 0.00
- pure red-cell aplasia · score 0.00
- periodontal disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P02814-F1 | alphafold | PREDICTED | 71.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P02814.
Amino-acid sequence (79 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMR3B?
The strongest Open Targets associations for SMR3B are eye infection, dental caries, hepatocellular carcinoma, neoplasm and small cell lung carcinoma.
How long is the SMR3B protein?
The Homo sapiens SMR3B protein (UniProt P02814) is 79 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P02814 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P02814 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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