Calcitonin gene-related peptide 1 (CALCA)
Homo sapiens — UniProt P06881
Data last refreshed: (UniProt release unknown)
Key facts
Calcitonin gene-related peptide 1 (CALCA) is a protein from Homo sapiens identified by UniProt accession P06881, 128 residues long. MolForge cross-references it against 3 known binders and 0 disease associations.
- UniProt accession: P06881; gene symbol CALCA.
- Organism: Homo sapiens.
- Length: 128 amino acids.
- Approved drugs acting on it (DrugCentral): Eptinezumab, Fremanezumab and Galcanezumab.
Target properties
| Protein name | Calcitonin gene-related peptide 1 |
|---|---|
| UniProt accession | P06881 |
| Gene | CALCA |
| Organism | Homo sapiens |
| Length | 128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). Approved drug exists
| Druggability tier | — |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Approved drugs acting on this target (3)
Approved drugs whose DrugCentral mechanism of action is this protein, most potent first.
3D Structure
Predicted structure for P06881 is available from the AlphaFold Protein Structure Database.
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P06881.
Amino-acid sequence (128 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which approved drugs target CALCA?
DrugCentral lists 3 approved drugs whose mechanism of action is CALCA: Eptinezumab, Fremanezumab and Galcanezumab.
How long is the CALCA protein?
The Homo sapiens CALCA protein (UniProt P06881) is 128 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P06881 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P06881 — predicted 3D structure (CC BY 4.0)
- DrugCentral — approved drugs and mechanism-of-action links (CC BY-SA 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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