U2 small nuclear ribonucleoprotein B'' (SNRPB2)
Homo sapiens — UniProt P08579
Data last refreshed: (UniProt release unknown)
Key facts
U2 small nuclear ribonucleoprotein B'' (SNRPB2) is a protein from Homo sapiens identified by UniProt accession P08579, 225 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: P08579; gene symbol SNRPB2.
- Organism: Homo sapiens.
- Length: 225 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, protein measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | U2 small nuclear ribonucleoprotein B'' |
|---|---|
| UniProt accession | P08579 |
| Gene | SNRPB2 |
| Organism | Homo sapiens |
| Length | 225 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- protein measurement · score 0.13
- blood protein measurement · score 0.11
- glycine measurement · score 0.10
- cortical surface area measurement · score 0.09
- neuroimaging measurement · score 0.08
- cortical thickness · score 0.08
- brain measurement · score 0.08
- mean platelet volume · score 0.07
- surgery on leg artery · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P08579-F1 | alphafold | PREDICTED | 82.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P08579.
Amino-acid sequence (225 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRPB2?
The strongest Open Targets associations for SNRPB2 are neurodegenerative disease, protein measurement, blood protein measurement, glycine measurement and cortical surface area measurement.
How long is the SNRPB2 protein?
The Homo sapiens SNRPB2 protein (UniProt P08579) is 225 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P08579 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P08579 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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