U1 small nuclear ribonucleoprotein A (SNRPA)
Homo sapiens — UniProt P09012
Data last refreshed: (UniProt release unknown)
Key facts
U1 small nuclear ribonucleoprotein A (SNRPA) is a protein from Homo sapiens identified by UniProt accession P09012, 282 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: P09012; gene symbol SNRPA.
- Organism: Homo sapiens.
- Length: 282 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroinflammatory disorder and melanoma-derived growth regulatory protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | U1 small nuclear ribonucleoprotein A |
|---|---|
| UniProt accession | P09012 |
| Gene | SNRPA |
| Organism | Homo sapiens |
| Length | 282 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- neuroinflammatory disorder · score 0.32
- melanoma-derived growth regulatory protein measurement · score 0.15
- blood protein measurement · score 0.11
- protein measurement · score 0.09
- hepatocellular carcinoma · score 0.09
- erythrocyte count · score 0.09
- lung adenocarcinoma · score 0.08
- eosinophil percentage of leukocytes · score 0.07
- systemic scleroderma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P09012-F1 | alphafold | PREDICTED | 79.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P09012.
Amino-acid sequence (282 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRPA?
The strongest Open Targets associations for SNRPA are neurodegenerative disease, neuroinflammatory disorder, melanoma-derived growth regulatory protein measurement, blood protein measurement and protein measurement.
How long is the SNRPA protein?
The Homo sapiens SNRPA protein (UniProt P09012) is 282 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P09012 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P09012 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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