Glutathione S-transferase P (GSTP1)

About Glutathione S-transferase P

Glutathione S-transferase P (GSTP1) is a protein from Homo sapiens identified by UniProt accession P09211, 210 residues long. MolForge cross-references it against 0 known binders and 602 disease associations.

Target properties

Protein name	Glutathione S-transferase P
UniProt accession	P09211
Gene	GSTP1
Organism	Homo sapiens
Length	210 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (4)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (602)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.35
breast adenocarcinoma · score 0.18
myelodysplastic syndrome · score 0.12
hypertrophic cardiomyopathy · score 0.11
hepatocellular carcinoma · score 0.11
non-small cell lung carcinoma · score 0.10
breast cancer · score 0.10
cancer · score 0.10
chronic obstructive pulmonary disease · score 0.10
urinary metabolite measurement · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09211-F1	alphafold	PREDICTED	98.01	—

Amino-acid sequence (210 residues)

MPPYTVVYFP VRGRCAALRM LLADQGQSWK EEVVTVETWQ EGSLKASCLY GQLPKFQDGD LTLYQSNTIL RHLGRTLGLY GKDQQEAALV DMVNDGVEDL RCKYISLIYT NYEAGKDDYV KALPGQLKPF ETLLSQNQGG KTFIVGDQIS FADYNLLDLL LIHEVLAPGC LDAFPLLSAY VGRLSARPKL KAFLASPEYV NLPINGNGKQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards