Tocofersolan

ALIMENTARY TRACT AND METABOLISM

Key facts

Tocofersolan is an ofp drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including GSTP1 and TTPA. Recorded indications include Obstruction of bile duct and Vitamin E deficiency.

• Approval status: ofp.
• Molecular targets: GSTP1 and TTPA (2 listed in DrugCentral).
• Indications: Obstruction of bile duct and Vitamin E deficiency.
• ATC code: A11HA08 (Other plain vitamin preparations).
• Molecular formula: C29H50O2; molecular weight 430.72 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (2)

• Obstruction of bile duct
• Vitamin E deficiency

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Glutathione S-transferase P	GSTP1	unknown	IC50 6.30
Alpha-tocopherol transfer protein	TTPA	unknown	Kd 5.62

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
A11HA08	ALIMENTARY TRACT AND METABOLISM › VITAMINS › OTHER PLAIN VITAMIN PREPARATIONS › Other plain vitamin preparations

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Macular degeneration	485.4
Appendicolith	268.7
Therapy cessation	241.0
Blood uric acid increased	232.4
Blood phosphorus increased	222.0
Chronic sinusitis	206.6
Electric shock	191.2
Appendicitis	181.7
Paraesthesia oral	168.1
Vaginal flatulence	164.6
Procedural pain	156.1
Constipation	151.5

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Tocofersolan is on its molecule page.

• Molecular formula: C₂₉H₅₀O₂
• Molecular weight: 430.72 g/mol
• CAS number: —
• InChIKey: GVJHHUAWPYXKBD-IEOSBIPESA-N
• PubChem CID: 14985

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Tocofersolan used for?

DrugCentral lists the following indications for Tocofersolan: Obstruction of bile duct and Vitamin E deficiency.

How does Tocofersolan work?

Its molecular targets in DrugCentral include GSTP1 and TTPA.

What is the chemical formula of Tocofersolan?

Tocofersolan has the molecular formula C29H50O2 and a molecular weight of 430.72 g/mol.

Sources

• DrugCentral drug card 4280 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2108106 — compound record and bioactivity
• PubChem CID 14985 — chemical identifiers
• DrugBank DB00163 — drug record
• FDA UNII N9PR3490H9 — substance identity
• DailyMed: FDA labels for Tocofersolan — current prescribing information (label search)
• UniProt P09211 (GSTP1) — target protein
• UniProt P49638 (TTPA) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.