Dexpanthenol

ALIMENTARY TRACT AND METABOLISM

Key facts

Dexpanthenol is an ofp drug catalogued in DrugCentral. It was first approved by the FDA in 1953. Recorded indications include Arthropod bite wound, Contact dermatitis due to poison oak, Diaper rash and Disorder of skin.

• Approval status: ofp (first approved 1953 by the FDA).
• Indications: Arthropod bite wound, Contact dermatitis due to poison oak, Diaper rash, Disorder of skin and Eczema and others.
• ATC code: A11HA30 (Other plain vitamin preparations).
• Molecular formula: C9H19NO4; molecular weight 205.25 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (9)

• Arthropod bite wound
• Contact dermatitis due to poison oak
• Diaper rash
• Disorder of skin
• Eczema
• Gastroparesis
• Paralytic ileus
• Paralytic Ileus Prevention
• Toxicodendron radicans

Off-label uses (4)

• Chafing of skin
• Eruption of skin
• Itching of skin
• Skin irritation

Contraindications (1)

• Hemophilia

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1953-02-20	FDA	—	HOSPIRA

ATC classification

ATC code	Therapeutic hierarchy
A11HA30	ALIMENTARY TRACT AND METABOLISM › VITAMINS › OTHER PLAIN VITAMIN PREPARATIONS › Other plain vitamin preparations
D03AX03	DERMATOLOGICALS › PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS › CICATRIZANTS › Other cicatrizants
S01XA12	SENSORY ORGANS › OPHTHALMOLOGICALS › OTHER OPHTHALMOLOGICALS › Other ophthalmologicals

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Pneumonia aspiration	176.8
Gastrooesophageal reflux disease	173.7
Coma	116.9
Female genital tract fistula	92.0
Somnolence	89.0
Vaginal flatulence	80.5
Chronic sinusitis	78.0
Toxic epidermal necrolysis	76.7
Epidermal necrosis	70.8
Proctitis	69.7
Radiculopathy	67.5
Vaginal discharge	65.8

Chemical structure

• Molecular formula: C₉H₁₉NO₄
• Molecular weight: 205.25 g/mol
• CAS number: 81-13-0
• InChIKey: SNPLKNRPJHDVJA-ZETCQYMHSA-N
• PubChem CID: 131204

CC(C)(CO)[C@@H](O)C(=O)NCCCO

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Dexpanthenol used for?

DrugCentral lists the following indications for Dexpanthenol: Arthropod bite wound, Contact dermatitis due to poison oak, Diaper rash, Disorder of skin, Eczema, Gastroparesis, Paralytic ileus and Paralytic Ileus Prevention and others.

When was Dexpanthenol first approved?

Dexpanthenol was first approved by the FDA in 1953.

What is the chemical formula of Dexpanthenol?

Dexpanthenol has the molecular formula C9H19NO4 and a molecular weight of 205.25 g/mol.

Sources

• DrugCentral drug card 838 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200979 — compound record and bioactivity
• PubChem CID 131204 — chemical identifiers
• DrugBank DB09357 — drug record
• FDA UNII 1O6C93RI7Z — substance identity
• DailyMed: FDA labels for Dexpanthenol — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.