Vitamin E
ALIMENTARY TRACT AND METABOLISM
Also known as: Tocofer 400, tocopherol (vit E)
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Vitamin E is a drug catalogued in DrugCentral. It was first approved by the FDA in 1953. DrugCentral lists 2 molecular targets, including GSTP1 and TTPA. Recorded indications include Vitamin E deficiency.
- Molecular targets: GSTP1 and TTPA (2 listed in DrugCentral).
- Indications: Vitamin E deficiency.
- ATC code: A11HA03 (Other plain vitamin preparations).
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Vitamin E deficiency
Mechanism & targets
Molecular targets (2)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Glutathione S-transferase P | GSTP1 | unknown | IC50 6.30 |
| Alpha-tocopherol transfer protein | TTPA | unknown | Kd 5.62 |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1953-02-20 | FDA | — | HOSPIRA |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
A11HA03 | ALIMENTARY TRACT AND METABOLISM › VITAMINS › OTHER PLAIN VITAMIN PREPARATIONS › Other plain vitamin preparations |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Vitamin E is on its molecule page.
| Molecular formula | — |
|---|---|
| Molecular weight | — |
| CAS number | — |
| InChIKey | — |
| PubChem CID | 14985 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Vitamin E used for?
DrugCentral lists the following indications for Vitamin E: Vitamin E deficiency.
How does Vitamin E work?
Its molecular targets in DrugCentral include GSTP1 and TTPA.
When was Vitamin E first approved?
Vitamin E was first approved by the FDA in 1953.
Browse: all drugs starting with V · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 3613 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL3989727 — compound record and bioactivity
- PubChem CID 14985 — chemical identifiers
- DrugBank DB00163 — drug record
- DailyMed: FDA labels for Vitamin E — current prescribing information (label search)
- UniProt P09211 (GSTP1) — target protein
- UniProt P49638 (TTPA) — target protein
How this page is built: methodology · editorial policy & corrections.
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