U2 small nuclear ribonucleoprotein A' (SNRPA1)
Homo sapiens — UniProt P09661
Data last refreshed: (UniProt release unknown)
Key facts
U2 small nuclear ribonucleoprotein A' (SNRPA1) is a protein from Homo sapiens identified by UniProt accession P09661, 255 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: P09661; gene symbol SNRPA1.
- Organism: Homo sapiens.
- Length: 255 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | U2 small nuclear ribonucleoprotein A' |
|---|---|
| UniProt accession | P09661 |
| Gene | SNRPA1 |
| Organism | Homo sapiens |
| Length | 255 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- body height · score 0.09
- cancer · score 0.08
- neoplasm · score 0.08
- hepatocellular carcinoma · score 0.08
- nonpapillary renal cell carcinoma · score 0.07
- lung adenocarcinoma · score 0.07
- handedness · score 0.07
- low density lipoprotein cholesterol measurement · score 0.06
- neutrophil count · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P09661-F1 | alphafold | PREDICTED | 87.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P09661.
Amino-acid sequence (255 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRPA1?
The strongest Open Targets associations for SNRPA1 are neurodegenerative disease, body height, cancer, neoplasm and hepatocellular carcinoma.
How long is the SNRPA1 protein?
The Homo sapiens SNRPA1 protein (UniProt P09661) is 255 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P09661 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P09661 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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