Putative protein N-methyltransferase FAM86B2 (FAM86B2)
Homo sapiens — UniProt P0C5J1
Data last refreshed: (UniProt release unknown)
Key facts
Putative protein N-methyltransferase FAM86B2 (FAM86B2) is a protein from Homo sapiens identified by UniProt accession P0C5J1, 330 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: P0C5J1; gene symbol FAM86B2.
- Organism: Homo sapiens.
- Length: 330 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, MODY and diabetes mellitus, transient neonatal, 2.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative protein N-methyltransferase FAM86B2 |
|---|---|
| UniProt accession | P0C5J1 |
| Gene | FAM86B2 |
| Organism | Homo sapiens |
| Length | 330 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.22
- MODY · score 0.08
- diabetes mellitus, transient neonatal, 2 · score 0.05
- eosinophil percentage of leukocytes · score 0.04
- butyrylcholinesterase deficiency · score 0.04
- refractive error measurement · score 0.02
- Red cell distribution width · score 0.02
- neuroticism measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0C5J1-F1 | alphafold | PREDICTED | 89.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0C5J1.
Amino-acid sequence (330 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM86B2?
The strongest Open Targets associations for FAM86B2 are gut microbiome measurement, MODY, diabetes mellitus, transient neonatal, 2, eosinophil percentage of leukocytes and butyrylcholinesterase deficiency.
How long is the FAM86B2 protein?
The Homo sapiens FAM86B2 protein (UniProt P0C5J1) is 330 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0C5J1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0C5J1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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