Transmembrane protein 191B (TMEM191B)
Homo sapiens — UniProt P0C7N4
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 191B (TMEM191B) is a protein from Homo sapiens identified by UniProt accession P0C7N4, 346 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: P0C7N4; gene symbol TMEM191B.
- Organism: Homo sapiens.
- Length: 346 amino acids.
- Top disease associations (Open Targets): platelet crit, secondary progressive multiple sclerosis and meningeal tuberculosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 191B |
|---|---|
| UniProt accession | P0C7N4 |
| Gene | TMEM191B |
| Organism | Homo sapiens |
| Length | 346 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- platelet crit · score 0.03
- secondary progressive multiple sclerosis · score 0.00
- meningeal tuberculosis · score 0.00
- chronic kidney disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0C7N4-F1 | alphafold | PREDICTED | 73.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0C7N4.
Amino-acid sequence (346 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM191B?
The strongest Open Targets associations for TMEM191B are platelet crit, secondary progressive multiple sclerosis, meningeal tuberculosis and chronic kidney disease.
How long is the TMEM191B protein?
The Homo sapiens TMEM191B protein (UniProt P0C7N4) is 346 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0C7N4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0C7N4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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