Putative inactive neutral ceramidase B (ASAH2B)

About Putative inactive neutral ceramidase B

Putative inactive neutral ceramidase B (ASAH2B) is a protein from Homo sapiens identified by UniProt accession P0C7U1, 165 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Putative inactive neutral ceramidase B
UniProt accession	P0C7U1
Gene	ASAH2B
Organism	Homo sapiens
Length	165 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

urate measurement · score 0.35
creatinine measurement · score 0.35
glomerular filtration rate · score 0.34
low density lipoprotein cholesterol measurement · score 0.34
serum gamma-glutamyl transferase measurement · score 0.28
apolipoprotein B measurement · score 0.27
triglyceride measurement · score 0.27
total blood protein measurement · score 0.27
total cholesterol measurement · score 0.27
calcium measurement · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P0C7U1-F1	alphafold	PREDICTED	86.62	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0C7U1.

Amino-acid sequence (165 residues)

MRQHRQFMDR THYLLTFSSS ETLLRLLLRI VDRAPKGRTF GDVLQPAKPE YRVGEVAEVI FVGANPKNSV QNQTHQTFLT VEKYEATSTS WQIVCNDASW ETRFYWHKGL LGLSNATVEW HIPDTAQPGI YRIRYFGHNR KQDILKPAVI LSFEGTSPAF EVVTI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards