Transcription factor SPT20 homolog-like 2 (SUPT20HL2)
Homo sapiens — UniProt P0C7V6
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SPT20 homolog-like 2 (SUPT20HL2) is a protein from Homo sapiens identified by UniProt accession P0C7V6, 817 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.
- UniProt accession: P0C7V6; gene symbol SUPT20HL2.
- Organism: Homo sapiens.
- Length: 817 amino acids.
- Top disease associations (Open Targets): craniodiaphyseal dysplasia and Bardet-Biedl syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SPT20 homolog-like 2 |
|---|---|
| UniProt accession | P0C7V6 |
| Gene | SUPT20HL2 |
| Organism | Homo sapiens |
| Length | 817 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (2)
Diseases linked to this target (Open Targets).
- craniodiaphyseal dysplasia · score 0.00
- Bardet-Biedl syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0C7V6-F1 | alphafold | PREDICTED | 50.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0C7V6.
Amino-acid sequence (817 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SUPT20HL2?
The strongest Open Targets associations for SUPT20HL2 are craniodiaphyseal dysplasia and Bardet-Biedl syndrome.
How long is the SUPT20HL2 protein?
The Homo sapiens SUPT20HL2 protein (UniProt P0C7V6) is 817 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0C7V6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0C7V6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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