Transcription factor Sp9 (SP9)
Homo sapiens — UniProt P0CG40
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor Sp9 (SP9) is a protein from Homo sapiens identified by UniProt accession P0CG40, 484 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: P0CG40; gene symbol SP9.
- Organism: Homo sapiens.
- Length: 484 amino acids.
- Top disease associations (Open Targets): Intellectual disability, Autistic behavior and EEG abnormality.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor Sp9 |
|---|---|
| UniProt accession | P0CG40 |
| Gene | SP9 |
| Organism | Homo sapiens |
| Length | 484 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- Intellectual disability · score 0.46
- Autistic behavior · score 0.42
- EEG abnormality · score 0.40
- Hypotonia · score 0.40
- self reported educational attainment · score 0.37
- Convulsive status epilepticus · score 0.33
- Epileptic spasm · score 0.33
- Epileptic encephalopathy · score 0.32
- body fat percentage · score 0.31
- body mass index · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0CG40-F1 | alphafold | PREDICTED | 48.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0CG40.
Amino-acid sequence (484 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SP9?
The strongest Open Targets associations for SP9 are Intellectual disability, Autistic behavior, EEG abnormality, Hypotonia and self reported educational attainment.
How long is the SP9 protein?
The Homo sapiens SP9 protein (UniProt P0CG40) is 484 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0CG40 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0CG40 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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