Speedy protein E6 (SPDYE6)
Homo sapiens — UniProt P0CI01
Data last refreshed: (UniProt release unknown)
Key facts
Speedy protein E6 (SPDYE6) is a protein from Homo sapiens identified by UniProt accession P0CI01, 402 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: P0CI01; gene symbol SPDYE6.
- Organism: Homo sapiens.
- Length: 402 amino acids.
- Top disease associations (Open Targets): chronotype measurement, mean platelet volume and neuronal ceroid lipofuscinosis 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speedy protein E6 |
|---|---|
| UniProt accession | P0CI01 |
| Gene | SPDYE6 |
| Organism | Homo sapiens |
| Length | 402 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.07
- mean platelet volume · score 0.06
- neuronal ceroid lipofuscinosis 1 · score 0.03
- platelet component distribution width · score 0.03
- blood phosphate measurement · score 0.02
- insomnia measurement · score 0.02
- BMI-adjusted waist-hip ratio · score 0.02
- insomnia · score 0.00
- Friedreich ataxia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0CI01-F1 | alphafold | PREDICTED | 60.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0CI01.
Amino-acid sequence (402 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPDYE6?
The strongest Open Targets associations for SPDYE6 are chronotype measurement, mean platelet volume, neuronal ceroid lipofuscinosis 1, platelet component distribution width and blood phosphate measurement.
How long is the SPDYE6 protein?
The Homo sapiens SPDYE6 protein (UniProt P0CI01) is 402 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0CI01 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0CI01 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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