Protein RD3-like (RD3L)
Homo sapiens — UniProt P0DJH9
Data last refreshed: (UniProt release unknown)
Key facts
Protein RD3-like (RD3L) is a protein from Homo sapiens identified by UniProt accession P0DJH9, 198 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: P0DJH9; gene symbol RD3L.
- Organism: Homo sapiens.
- Length: 198 amino acids.
- Top disease associations (Open Targets): refractive error, ganglion cell inner plexiform layer thickness measurement and retinal layer thickness measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein RD3-like |
|---|---|
| UniProt accession | P0DJH9 |
| Gene | RD3L |
| Organism | Homo sapiens |
| Length | 198 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- refractive error · score 0.24
- ganglion cell inner plexiform layer thickness measurement · score 0.23
- retinal layer thickness measurement · score 0.22
- Abnormality of refraction · score 0.20
- Myopia · score 0.19
- age at onset · score 0.19
- unipolar depression · score 0.06
- alcohol use disorder measurement · score 0.04
- adolescent idiopathic scoliosis · score 0.03
- blood metabolite measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0DJH9-F1 | alphafold | PREDICTED | 73.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0DJH9.
Amino-acid sequence (198 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RD3L?
The strongest Open Targets associations for RD3L are refractive error, ganglion cell inner plexiform layer thickness measurement, retinal layer thickness measurement, Abnormality of refraction and Myopia.
How long is the RD3L protein?
The Homo sapiens RD3L protein (UniProt P0DJH9) is 198 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0DJH9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0DJH9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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