Small integral membrane protein 17 (SMIM17)
Homo sapiens — UniProt P0DL12
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 17 (SMIM17) is a protein from Homo sapiens identified by UniProt accession P0DL12, 118 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: P0DL12; gene symbol SMIM17.
- Organism: Homo sapiens.
- Length: 118 amino acids.
- Top disease associations (Open Targets): visual perception measurement, astrocytoma and ependymoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 17 |
|---|---|
| UniProt accession | P0DL12 |
| Gene | SMIM17 |
| Organism | Homo sapiens |
| Length | 118 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- visual perception measurement · score 0.04
- astrocytoma · score 0.03
- ependymoma · score 0.02
- glioblastoma multiforme · score 0.02
- oligodendroglioma · score 0.02
- large cell medulloblastoma · score 0.02
- atypical teratoid rhabdoid tumor · score 0.01
- medulloblastoma · score 0.01
- Pick disease · score 0.00
- Alzheimer disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0DL12-F1 | alphafold | PREDICTED | 59.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0DL12.
Amino-acid sequence (118 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM17?
The strongest Open Targets associations for SMIM17 are visual perception measurement, astrocytoma, ependymoma, glioblastoma multiforme and oligodendroglioma.
How long is the SMIM17 protein?
The Homo sapiens SMIM17 protein (UniProt P0DL12) is 118 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0DL12 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0DL12 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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