Small integral membrane protein 10-like protein 1 (SMIM10L1)
Homo sapiens — UniProt P0DMW3
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 10-like protein 1 (SMIM10L1) is a protein from Homo sapiens identified by UniProt accession P0DMW3, 68 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: P0DMW3; gene symbol SMIM10L1.
- Organism: Homo sapiens.
- Length: 68 amino acids.
- Top disease associations (Open Targets): blood protein measurement, juvenile dermatomyositis and Alzheimer disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 10-like protein 1 |
|---|---|
| UniProt accession | P0DMW3 |
| Gene | SMIM10L1 |
| Organism | Homo sapiens |
| Length | 68 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.05
- juvenile dermatomyositis · score 0.01
- Alzheimer disease · score 0.00
- acute quadriplegic myopathy · score 0.00
- PTEN hamartoma tumor syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0DMW3-F1 | alphafold | PREDICTED | 68.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0DMW3.
Amino-acid sequence (68 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM10L1?
The strongest Open Targets associations for SMIM10L1 are blood protein measurement, juvenile dermatomyositis, Alzheimer disease, acute quadriplegic myopathy and PTEN hamartoma tumor syndrome.
How long is the SMIM10L1 protein?
The Homo sapiens SMIM10L1 protein (UniProt P0DMW3) is 68 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0DMW3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0DMW3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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