Small integral membrane protein 10-like protein 2A (SMIM10L2A)
Homo sapiens — UniProt P0DMW4
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 10-like protein 2A (SMIM10L2A) is a protein from Homo sapiens identified by UniProt accession P0DMW4, 78 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: P0DMW4; gene symbol SMIM10L2A.
- Organism: Homo sapiens.
- Length: 78 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, astrocytoma and breast carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 10-like protein 2A |
|---|---|
| UniProt accession | P0DMW4 |
| Gene | SMIM10L2A |
| Organism | Homo sapiens |
| Length | 78 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.04
- astrocytoma · score 0.02
- breast carcinoma · score 0.02
- atypical teratoid rhabdoid tumor · score 0.02
- large cell medulloblastoma · score 0.02
- oligodendroglioma · score 0.02
- psoriasis · score 0.01
- medulloblastoma · score 0.01
- neoplasm · score 0.01
- pituitary cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0DMW4-F1 | alphafold | PREDICTED | 67.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0DMW4.
Amino-acid sequence (78 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM10L2A?
The strongest Open Targets associations for SMIM10L2A are glioblastoma multiforme, astrocytoma, breast carcinoma, atypical teratoid rhabdoid tumor and large cell medulloblastoma.
How long is the SMIM10L2A protein?
The Homo sapiens SMIM10L2A protein (UniProt P0DMW4) is 78 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0DMW4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0DMW4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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