Small integral membrane protein 10-like protein 2B (SMIM10L2B)
Homo sapiens — UniProt P0DMW5
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 10-like protein 2B (SMIM10L2B) is a protein from Homo sapiens identified by UniProt accession P0DMW5, 78 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: P0DMW5; gene symbol SMIM10L2B.
- Organism: Homo sapiens.
- Length: 78 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, central nervous system cancer and gonorrhea.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 10-like protein 2B |
|---|---|
| UniProt accession | P0DMW5 |
| Gene | SMIM10L2B |
| Organism | Homo sapiens |
| Length | 78 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.03
- central nervous system cancer · score 0.03
- gonorrhea · score 0.01
- breast carcinoma · score 0.01
- papillary thyroid carcinoma · score 0.01
- esophageal squamous cell carcinoma · score 0.00
- cancer · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0DMW5-F1 | alphafold | PREDICTED | 65.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0DMW5.
Amino-acid sequence (78 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM10L2B?
The strongest Open Targets associations for SMIM10L2B are glioblastoma multiforme, central nervous system cancer, gonorrhea, breast carcinoma and papillary thyroid carcinoma.
How long is the SMIM10L2B protein?
The Homo sapiens SMIM10L2B protein (UniProt P0DMW5) is 78 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0DMW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0DMW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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