Probable non-functional immunoglobulin kappa variable 1D-37 (IGKV1D-37)
Homo sapiens — UniProt P0DSN7
Data last refreshed: (UniProt release unknown)
Key facts
Probable non-functional immunoglobulin kappa variable 1D-37 (IGKV1D-37) is a protein from Homo sapiens identified by UniProt accession P0DSN7, 117 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: P0DSN7; gene symbol IGKV1D-37.
- Organism: Homo sapiens.
- Length: 117 amino acids.
- Top disease associations (Open Targets): neoplasm, Salmonella Infections and multiple system atrophy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable non-functional immunoglobulin kappa variable 1D-37 |
|---|---|
| UniProt accession | P0DSN7 |
| Gene | IGKV1D-37 |
| Organism | Homo sapiens |
| Length | 117 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | LOW |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.01
- Salmonella Infections · score 0.01
- multiple system atrophy · score 0.01
- multiple sclerosis · score 0.01
- experimental autoimmune encephalomyelitis · score 0.01
- periventricular leukomalacia · score 0.01
- primary progressive multiple sclerosis · score 0.00
- myeloid sarcoma · score 0.00
- infection · score 0.00
- infect · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0DSN7-F1 | alphafold | PREDICTED | 88.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0DSN7.
Amino-acid sequence (117 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGKV1D-37?
The strongest Open Targets associations for IGKV1D-37 are neoplasm, Salmonella Infections, multiple system atrophy, multiple sclerosis and experimental autoimmune encephalomyelitis.
How long is the IGKV1D-37 protein?
The Homo sapiens IGKV1D-37 protein (UniProt P0DSN7) is 117 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0DSN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0DSN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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