Speedy protein E18 (SPDYE18)
Homo sapiens — UniProt P0DV79
Data last refreshed: (UniProt release unknown)
Key facts
Speedy protein E18 (SPDYE18) is a protein from Homo sapiens identified by UniProt accession P0DV79, 352 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: P0DV79; gene symbol SPDYE18.
- Organism: Homo sapiens.
- Length: 352 amino acids.
- Top disease associations (Open Targets): body mass index, osteoarthritis and obesity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Speedy protein E18 |
|---|---|
| UniProt accession | P0DV79 |
| Gene | SPDYE18 |
| Organism | Homo sapiens |
| Length | 352 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- body mass index · score 0.42
- osteoarthritis · score 0.32
- obesity · score 0.29
- waist circumference · score 0.28
- waist-hip ratio · score 0.27
- physical activity measurement · score 0.26
- smoking behavior · score 0.26
- lean body mass · score 0.23
- fat body mass · score 0.22
- bipolar disorder · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P0DV79-F1 | alphafold | PREDICTED | 61.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P0DV79.
Amino-acid sequence (352 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPDYE18?
The strongest Open Targets associations for SPDYE18 are body mass index, osteoarthritis, obesity, waist circumference and waist-hip ratio.
How long is the SPDYE18 protein?
The Homo sapiens SPDYE18 protein (UniProt P0DV79) is 352 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P0DV79 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P0DV79 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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