Transcription factor SOX-5 (SOX5)
Homo sapiens — UniProt P35711
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-5 (SOX5) is a protein from Homo sapiens identified by UniProt accession P35711, 763 residues long. MolForge cross-references it against 0 known binders and 297 disease associations.
- UniProt accession: P35711; gene symbol SOX5.
- Organism: Homo sapiens.
- Length: 763 amino acids.
- Top disease associations (Open Targets): developmental and speech delay due to SOX5 deficiency, genetic disorder and electrocardiography.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-5 |
|---|---|
| UniProt accession | P35711 |
| Gene | SOX5 |
| Organism | Homo sapiens |
| Length | 763 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (297)
Diseases linked to this target (Open Targets).
- developmental and speech delay due to SOX5 deficiency · score 0.72
- genetic disorder · score 0.52
- electrocardiography · score 0.46
- lean body mass · score 0.44
- body mass index · score 0.44
- body height · score 0.43
- osteoarthritis, knee · score 0.43
- unipolar depression · score 0.43
- PR interval · score 0.42
- heart rate response to recovery post exercise · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P35711-F1 | alphafold | PREDICTED | 57.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P35711.
Amino-acid sequence (763 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX5?
The strongest Open Targets associations for SOX5 are developmental and speech delay due to SOX5 deficiency, genetic disorder, electrocardiography, lean body mass and body mass index.
How long is the SOX5 protein?
The Homo sapiens SOX5 protein (UniProt P35711) is 763 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P35711 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P35711 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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