Transcription factor SOX-6 (SOX6)
Homo sapiens — UniProt P35712
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-6 (SOX6) is a protein from Homo sapiens identified by UniProt accession P35712, 828 residues long. MolForge cross-references it against 0 known binders and 280 disease associations.
- UniProt accession: P35712; gene symbol SOX6.
- Organism: Homo sapiens.
- Length: 828 amino acids.
- Top disease associations (Open Targets): Tolchin-Le Caignec syndrome, mean corpuscular volume and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-6 |
|---|---|
| UniProt accession | P35712 |
| Gene | SOX6 |
| Organism | Homo sapiens |
| Length | 828 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (280)
Diseases linked to this target (Open Targets).
- Tolchin-Le Caignec syndrome · score 0.69
- mean corpuscular volume · score 0.51
- genetic disorder · score 0.51
- reticulocyte count · score 0.48
- craniosynostosis · score 0.46
- mean corpuscular hemoglobin · score 0.44
- Red cell distribution width · score 0.44
- heel bone mineral density · score 0.43
- mean corpuscular hemoglobin concentration · score 0.43
- diastolic blood pressure · score 0.43
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P35712-F1 | alphafold | PREDICTED | 55.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P35712.
Amino-acid sequence (828 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX6?
The strongest Open Targets associations for SOX6 are Tolchin-Le Caignec syndrome, mean corpuscular volume, genetic disorder, reticulocyte count and craniosynostosis.
How long is the SOX6 protein?
The Homo sapiens SOX6 protein (UniProt P35712) is 828 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P35712 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P35712 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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