Transcription factor SOX-11 (SOX11)
Homo sapiens — UniProt P35716
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor SOX-11 (SOX11) is a protein from Homo sapiens identified by UniProt accession P35716, 441 residues long. MolForge cross-references it against 0 known binders and 646 disease associations.
- UniProt accession: P35716; gene symbol SOX11.
- Organism: Homo sapiens.
- Length: 441 amino acids.
- Top disease associations (Open Targets): Coffin-Siris syndrome, neurodegenerative disease and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor SOX-11 |
|---|---|
| UniProt accession | P35716 |
| Gene | SOX11 |
| Organism | Homo sapiens |
| Length | 441 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (646)
Diseases linked to this target (Open Targets).
- Coffin-Siris syndrome · score 0.66
- neurodegenerative disease · score 0.56
- genetic disorder · score 0.49
- body mass index · score 0.40
- body height · score 0.38
- Neurodevelopmental disorder · score 0.38
- risk-taking behaviour · score 0.37
- multisite chronic pain · score 0.36
- age at first birth measurement · score 0.35
- appendicular lean mass · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P35716-F1 | alphafold | PREDICTED | 56.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P35716.
Amino-acid sequence (441 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SOX11?
The strongest Open Targets associations for SOX11 are Coffin-Siris syndrome, neurodegenerative disease, genetic disorder, body mass index and body height.
How long is the SOX11 protein?
The Homo sapiens SOX11 protein (UniProt P35716) is 441 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P35716 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P35716 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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