Sorting nexin-16 (SNX16)
Homo sapiens — UniProt P57768
Data last refreshed: (UniProt release unknown)
Key facts
Sorting nexin-16 (SNX16) is a protein from Homo sapiens identified by UniProt accession P57768, 344 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: P57768; gene symbol SNX16.
- Organism: Homo sapiens.
- Length: 344 amino acids.
- Top disease associations (Open Targets): mean platelet volume, hair color and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sorting nexin-16 |
|---|---|
| UniProt accession | P57768 |
| Gene | SNX16 |
| Organism | Homo sapiens |
| Length | 344 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.43
- hair color · score 0.40
- systolic blood pressure · score 0.34
- hypertension · score 0.34
- diastolic blood pressure · score 0.34
- cardiovascular disease · score 0.31
- hair colour measurement · score 0.27
- platelet count · score 0.26
- cortical thickness · score 0.23
- health study participation · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P57768-F1 | alphafold | PREDICTED | 70.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P57768.
Amino-acid sequence (344 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNX16?
The strongest Open Targets associations for SNX16 are mean platelet volume, hair color, systolic blood pressure, hypertension and diastolic blood pressure.
How long is the SNX16 protein?
The Homo sapiens SNX16 protein (UniProt P57768) is 344 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P57768 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P57768 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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