Taste receptor type 2 member 19 (TAS2R19)
Homo sapiens — UniProt P59542
Data last refreshed: (UniProt release unknown)
Key facts
Taste receptor type 2 member 19 (TAS2R19) is a protein from Homo sapiens identified by UniProt accession P59542, 299 residues long. MolForge cross-references it against 1 known binders and 16 disease associations.
- UniProt accession: P59542; gene symbol TAS2R19.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): lung adenocarcinoma, breast adenocarcinoma and squamous cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Taste receptor type 2 member 19 |
|---|---|
| UniProt accession | P59542 |
| Gene | TAS2R19 |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.16
- squamous cell lung carcinoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
- sensory perception of bitter taste · score 0.08
- blood protein measurement · score 0.05
- sebaceous of Jadassohn nevus · score 0.05
- breast carcinoma · score 0.04
- actinic keratosis · score 0.04
- coffee consumption measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P59542-F1 | alphafold | PREDICTED | 84.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P59542.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAS2R19?
The strongest Open Targets associations for TAS2R19 are lung adenocarcinoma, breast adenocarcinoma, squamous cell lung carcinoma, head and neck squamous cell carcinoma and sensory perception of bitter taste.
How long is the TAS2R19 protein?
The Homo sapiens TAS2R19 protein (UniProt P59542) is 299 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P59542 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P59542 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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