Small nuclear ribonucleoprotein E (SNRPE)
Homo sapiens — UniProt P62304
Data last refreshed: (UniProt release unknown)
Key facts
Small nuclear ribonucleoprotein E (SNRPE) is a protein from Homo sapiens identified by UniProt accession P62304, 92 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: P62304; gene symbol SNRPE.
- Organism: Homo sapiens.
- Length: 92 amino acids.
- Top disease associations (Open Targets): hypotrichosis simplex, Alzheimer disease and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small nuclear ribonucleoprotein E |
|---|---|
| UniProt accession | P62304 |
| Gene | SNRPE |
| Organism | Homo sapiens |
| Length | 92 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- hypotrichosis simplex · score 0.61
- Alzheimer disease · score 0.46
- Parkinson disease · score 0.46
- multiple sclerosis · score 0.46
- lysosomal storage disease · score 0.46
- neurodegenerative disease · score 0.46
- Red cell distribution width · score 0.09
- azoospermia · score 0.08
- spermatogenic failures 50 · score 0.06
- spermatogenic failure, X-linked, 2 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P62304-F1 | alphafold | PREDICTED | 90.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P62304.
Amino-acid sequence (92 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRPE?
The strongest Open Targets associations for SNRPE are hypotrichosis simplex, Alzheimer disease, Parkinson disease, multiple sclerosis and lysosomal storage disease.
How long is the SNRPE protein?
The Homo sapiens SNRPE protein (UniProt P62304) is 92 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P62304 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P62304 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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