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Small nuclear ribonucleoprotein Sm D1 (SNRPD1)

Homo sapiens — UniProt P62314

Gene: SNRPD1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Small nuclear ribonucleoprotein Sm D1 (SNRPD1) is a protein from Homo sapiens identified by UniProt accession P62314, 119 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

  • UniProt accession: P62314; gene symbol SNRPD1.
  • Organism: Homo sapiens.
  • Length: 119 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, neuroimaging measurement and brain volume measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSmall nuclear ribonucleoprotein Sm D1
UniProt accessionP62314
GeneSNRPD1
OrganismHomo sapiens
Length119 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (54)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.48
  • neuroimaging measurement · score 0.16
  • brain volume measurement · score 0.14
  • Systemic lupus erythematosus · score 0.09
  • brain measurement · score 0.08
  • hepatocellular carcinoma · score 0.07
  • appendicular lean mass · score 0.06
  • phospholipid measurement · score 0.06
  • phosphatidylcholine measurement · score 0.05
  • mean corpuscular volume · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P62314-F1alphafoldPREDICTED82.82—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for P62314.

Amino-acid sequence (119 residues)

MKLVRFLMKL SHETVTIELK NGTQVHGTIT GVDVSMNTHL KAVKMTLKNR EPVQLETLSI RGNNIRYFIL PDSLPLDTLL VDVEPKVKSK KREAVAGRGR GRGRGRGRGR GRGRGGPRR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SNRPD1?

The strongest Open Targets associations for SNRPD1 are neurodegenerative disease, neuroimaging measurement, brain volume measurement, Systemic lupus erythematosus and brain measurement.

How long is the SNRPD1 protein?

The Homo sapiens SNRPD1 protein (UniProt P62314) is 119 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtP62314
GeneSNRPD1
OrganismHomo sapiens
Length119
Binders0
Diseases54
View on UniProt