Small nuclear ribonucleoprotein Sm D2 (SNRPD2)
Homo sapiens — UniProt P62316
Data last refreshed: (UniProt release unknown)
Key facts
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) is a protein from Homo sapiens identified by UniProt accession P62316, 118 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: P62316; gene symbol SNRPD2.
- Organism: Homo sapiens.
- Length: 118 amino acids.
- Top disease associations (Open Targets): Alzheimer disease, Parkinson disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small nuclear ribonucleoprotein Sm D2 |
|---|---|
| UniProt accession | P62316 |
| Gene | SNRPD2 |
| Organism | Homo sapiens |
| Length | 118 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.44
- Parkinson disease · score 0.44
- multiple sclerosis · score 0.44
- lysosomal storage disease · score 0.44
- neurodegenerative disease · score 0.44
- hepatocellular carcinoma · score 0.09
- body mass index · score 0.08
- glucose measurement · score 0.08
- waist-hip ratio · score 0.08
- waist circumference · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P62316-F1 | alphafold | PREDICTED | 90.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P62316.
Amino-acid sequence (118 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRPD2?
The strongest Open Targets associations for SNRPD2 are Alzheimer disease, Parkinson disease, multiple sclerosis, lysosomal storage disease and neurodegenerative disease.
How long is the SNRPD2 protein?
The Homo sapiens SNRPD2 protein (UniProt P62316) is 118 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P62316 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P62316 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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