Small nuclear ribonucleoprotein Sm D3 (SNRPD3)
Homo sapiens — UniProt P62318
Data last refreshed: (UniProt release unknown)
Key facts
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) is a protein from Homo sapiens identified by UniProt accession P62318, 126 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: P62318; gene symbol SNRPD3.
- Organism: Homo sapiens.
- Length: 126 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small nuclear ribonucleoprotein Sm D3 |
|---|---|
| UniProt accession | P62318 |
| Gene | SNRPD3 |
| Organism | Homo sapiens |
| Length | 126 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- Alzheimer disease · score 0.46
- multiple sclerosis · score 0.46
- Parkinson disease · score 0.46
- lysosomal storage disease · score 0.46
- PHF-tau measurement · score 0.16
- neuroblastoma · score 0.07
- serum gamma-glutamyl transferase measurement · score 0.06
- diffuse plaque measurement · score 0.06
- alcoholic liver disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-P62318-F1 | alphafold | PREDICTED | 82.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for P62318.
Amino-acid sequence (126 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRPD3?
The strongest Open Targets associations for SNRPD3 are neurodegenerative disease, Alzheimer disease, multiple sclerosis, Parkinson disease and lysosomal storage disease.
How long is the SNRPD3 protein?
The Homo sapiens SNRPD3 protein (UniProt P62318) is 126 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB P62318 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB P62318 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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